This skincare line has serious science (think heat shock proteins, antioxidant balance technology, and iron chelation) in its corner. Dr. Luigi Polla is a pioneering dermatologist with a background in vascular skin conditions, while Dr. Barbara Polla is a biomedical researcher whose expertise runs the gamut from internal medicine to antiaging. In 1997, the husband-wife team founded Forever Laser Institut, a European medical day spa that inspired their botanical-based, clinically-tested products. The Pollas get pretty geeky about their skincare, but the foundation for their brand isn’t rocket science: Looking good means feeling good. In other words, handsomeness isn’t just skin deep.