This stuff is amazing. I am a life long acne sufferer, and I've tried everything under the sun. Nothing I have ever used has worked this effectively. My face is clearing up after 2 weeks of using this product and I am ecstatic. The product actually visibly reduces cystic acne. Large pimples go away after a few nights in a row with this spot treatment. Read the directions, do not use on broken skin! Good motivation to not pop your pimples. Only use it as a spot treatment. I use a different serum for my whole face, which I use on the nights I don't apply this spot treatment. This is a great value at $22 and I recommend it to anyone who thinks they've tried everything, because this one may just be the cure you've been looking for. Best thing I've bought from birchbox, and the best acne treatment I've ever had. I used to use retin-a, but I didn't want to go through the embarrassment of that starting to work. With this spot treatment, there is no awkward waiting period until it gets better. It just does!